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What Is a Very Premature Baby?


Updated June 02, 2014

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

Hispanic baby in intensive care unit
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Question: What Is a Very Premature Baby?
I was told I was at risk of having a very premature baby. I'm not sure what that means or what to expect if my baby is born early. Can you explain?

A premature baby is a baby born before 37 weeks gestation. Because babies grow so quickly during pregnancy, a premature baby born three to four months early is very different from one born three to four weeks early.

A baby born before 26 weeks gestation is called a micro preemie; a baby born between 34 and 37 weeks is a late preterm baby. This article focuses on premature babies who are born between 27 and 30 weeks gestation. Some people call these babies "very premature babies," and babies born between 31 and 34 weeks gestation "moderately preterm babies."

What Is the Survival Rate for a Very Premature Baby?

Over 95% of premature babies born between 27 and 30 weeks gestation survive. Although these babies are very immature and may face serious health problems, most of them recover from their premature birth with few long term effects of prematurity.

What Does a Very Premature Baby Look Like?

If you are visiting a very premature baby in the NICU, you may be surprised by how small the baby is. A baby born at 27 weeks weighs around 1000 grams (2 lbs 3 oz); a baby born at 30 weeks weighs around 1450 grams (3 lb 3 oz). Very premature babies have thin skin with visible veins, and have a lot of equipment present:

  • Respiratory support: Most very premature babies need respiratory support after birth. A very sick or immature baby may need mechanical ventilation. Other very premature babies may need CPAP or a nasal cannula.
  • IV lines: Due to immature digestive systems, very premature babies are fed by IV at first and introduced slowly to breast milk or formula. IV lines may come from the umbilical cord stump (umbilical catheters), or peripheral IVs or PICC lines may be placed in a premature baby's extremities or scalp.
  • NG/OG tubes: Before about 33 weeks gestation, babies cannot suck, swallow, and breathe at the same time. Very premature babies are fed through a tube that goes from the nose or mouth down into the stomach.
  • Monitoring equipment: Very premature babies will have stickers on their chests and wrists or feet to monitor their heart rate, breathing rate, and oxygen saturation.

Are There Health Problems in the NICU for Very Premature Babies?

A very premature baby may have a smooth NICU course or a complicated one. The most common health problems of very premature babies include:

  • Respiratory distress syndrome (RDS): About 70 to 85% of very premature babies need treatment for RDS. Respiratory distress is treated with respiratory support or medication.
  • Patent ductus arteriosus (PDA): Nearly half of 27 weekers and 17% of 29-30 weekers are born with a PDA. Although a PDA is normal in fetuses, this hole should close at birth. Medication or surgery can be used to close a PDA.
  • Sepsis: Because premature babies have immature immune systems, they are more susceptible to infection than term babies. About 25% of very premature babies need medication to treat infection.
  • Apnea of prematurity: Because their nervous systems are immature, premature babies may have periods of apnea or bradycardia. They usually outgrow this condition, which can be treated with medication, by the time they leave the NICU.
  • Anemia: Anemia, a lack of red blood cells, is common in premature babies. Anemia of prematurity is most often seen in babies born before 32 weeks, and may be treated with iron supplements, blood transfusions, or medications.
  • Intraventricular hemorrhage (IVH): Very premature babies have fragile blood vessels, especially in the brain. If these vessels break, blood may spill into the brain's ventricles. About 10% of very premature babies have a severe IVH.
  • Necrotizing enterocolitis (NEC): In NEC, the linings of the intestines become infected and begin to die. This is a serious condition that is treated with medication or surgery. Thankfully, only a small number (about 5%) of very premature babies suffer from NEC.

What Are Long Term Health Problems for a Very Premature Baby?

Most very premature babies recover from premature birth with few lasting effects. They may have special needs for the first few years, but usually outgrow their medical conditions over time. The most common long term health problems for very premature babies are:

  • Apnea of prematurity: Most very premature babies outgrow this before they leave the NICU, but others still have spells after they go home. These babies may go home with an apnea monitor to make sure they maintain their heart and breathing rates.
  • Chronic lung disease: Respiratory support can scar the lungs, causing chronic lung disease. About 1/3 of very premature babies need oxygen after NICU discharge, and many suffer from asthma or other respiratory illnesses as young children.
  • Developmental delay: Although severe cognitive disabilities are uncommon in very premature babies, developmental delay and trouble in school are more common. About 1/3 of very premature babies need some help in school as they get older.

How Can I Improve My Premature Baby's Outcome?

There are many things parents can do to help give their babies the best possible start:

  • Get early prenatal care: Early and regular prenatal care can help moms minimize their risks for premature birth and prevent or stop premature labor.
  • Pump breast milk: Even if moms don't plan to breastfeed, pumping breast milk even for a short time can help give very premature babies the best start.
  • Try kangaroo care: Bonding through kangaroo care can help premature babies grow and mature, and has many benefits for both parents and premature babies.
  • Seek early intervention: Many very premature babies will qualify for early intervention services. These state-run programs help very premature babies to catch up to their peers and meet milestones on time.


Marlow, N. "Neurocognitive Outcome After Very Preterm Birth." Archives of Disease in Childhood June 2003; 89, 224-228.

Qiu, X et al. "Comparison of Singleton and Multiple-Birth Outcomes of Infants Born at or Before 32 Weeks of Gestation." Obstetrics & Gynecology Feb 2008; 111, 365-371.

Vohr, B et al. "Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants <32 Weeks' Gestation Between 1993 and 1998." Pediatrics Sept 2005; 116, 635-643.

  1. About.com
  2. Health
  3. Preemies
  4. In the NICU
  5. FAQs About Having a Very Premature Baby

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